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Volume 02 - Issue 04 (December 2017)

Title: Variousapproachestowardstastemasking: Anoverview
Authors: Anuradha Keshawani, Adarsh Kesharwani, Manoj Kumar Mishra, Md. Amman Maqbool, Supriya Pathak, Pramod Kumar Biswal
Source: International Journal of Pharmaceutical Research and Applications, pp 01-09, Vol 02 - No. 04, December 2017
Abstract: Taste masking is the process of masking the bitter taste of drug for improving the patient compliance. As the taste masking is for all the drug but it is mainly seen in the drug of pediatric & geriatric patient. Taste maskingis improve by reducing the affinity o drug with taste receptor. Taste masking is done by application of polymer, amino acid, sweetening agent, & flavoring agent and also by removing of those group which are responsible for the bitter or unpleasant taste.To overcome this problem, many techniques have been developed to mask the bitter taste of drugs. These techniques are not only mask the bitter taste of drug but also enhance the bioavailability and performance of drug dosage form. It includes adding sugars, flavors, sweeteners, use of ipoproteins, numbing taste buds, granulation, use of adsorbates , coating drug, microencapsulation, multiple emulsion, viscosity modifier, vesicles and liposomes, prodrug and salt formation, inclusion and molecular complexes, solid dispersion and Ion Exchange Resins (IERs) which have been tried by the formulators to mask the unpleasant taste of the bitter drugs. The present review article highlights different technologies of taste masking with respect to dosage form and novel methods of evaluation of taste masking effect.
Keywords: Taste, Taste masking, Taste masking techniques, Taste evaluation, E-tongue
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Title: Ethnomedicobotanical Survey of Plants Used In the Treatment Of Different Ailments In Adoni Area
Authors: S.Swarupa Rani
Source: International Journal of Pharmaceutical Research and Applications, pp 10-13, Vol 02 - No. 04, December 2017
Abstract: Ethnomedico botanical survey was conducted in Adoni division focus on the identification and classification of medicinal plants along with ethnobotanical information. The present investigation was carried out from 2014 to 2015 mainly in Adoni area, yerukula, sugali, tanda tribes were identified. Necessary information was collected through interviews and iscussions with the local tribes and village elders. The information was collected about the plant names, local names, parts used mode of administration. Herbarium prepared and deposited in the Department of Botany. Nearly 40 medicinal plants were identified and medicinal uses were recorded. Some of the selected medicine plants were subjected to phytochemical screening for secondary metabolites. Soxhlet extraction methods were used by ethylalcohol, ether and water and results were recorded. Secondary metabolites like Alkaloids, flavanoids, tannins, saponins, phenols, terpenoids, coumarins, steroids etc., were identified. The results suggest that the phytochemical properties for curing various ailments and possess potential antioxidant and tends to the isolation of new and novel compounds.
Keywords: .................
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