| Title: |
Harmless Bacterial by Products for Chronic Wound Treatment.
A Clean Production Experience |
| Authors: |
Moreno, María Julieta || Cabrera, Carla Agostina || González Exequiel, Di Toto
Blessing, Lilian || Cerusico, Nicolás || Sesto Cabral, Maria Eugenia |
| Source: |
International Journal of Pharmaceutical Research and Applications, Volume 3, Issue 1 (June - 2018), PP. 01-11 |
| Abstract: |
Our research team develops topic formulations based on harmless bacterial by products for
chronic wound treatment. The entire scaling up process was designed to facilitate clinical trials, while Cleaner
Production (CP) technologies were implemented in order to improve the process. By defining our own critical
process points and increasing the efficiency of production processes, we expect reentering our own wastes in the
process line, to replace expensive constituents maintaining all pharmacological properties. Four new media were
designed and characterized, all activities previously reported were tested in vitro and a new quality control was
designed. It is possible by reentering in the process line to minimize environmental damage, to use resources
more efficiently; and to increase business profitability and competitiveness.In countries where research budgets
are meager as Argentina, the tendency to innovation and improvements in the designs prototypes ''made in
Argentina'' marks a growing trend adopted by researchers. The entering process and products were patented on
INPI (National Institute of Industrial Property), INPI AR20170123114. |
| Keywords: |
Culture media design, Lactobacillus plantarum, clean production, biofilm inhibition,
chronicwounds. |
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