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volume 3 ~ issue 2 (july 2018)

Title: The Neuropharmacological Potential And Pharmacognosy Of Evolvulus Alsinoides Linn.; An Overview
Authors: Deepika Chauhan || Raman Dang || Mahaveer Dhobi
Source: International Journal of Pharmaceutical Research and Applications, Volume 3, Issue 2 (July) 2018), PP. 01-06
Abstract: The modern treatments for CNS disorders have shown a number of problems in terms of safety, efficacy and side effects. Hence, an alternative to synthetic drugs is required for the benefit of patients suffering from neurological disorders. The prevalence rates of the spectrum of neurological disorders from different regions of the country ranged from 967-4,070 with a mean of 2394 per 100,000 population, providing a rough estimate of over 30 million people with neurological disorders (excluding neuroinfections and traumatic injuries). Evolvulus alsinoides L. commonly known as Shankhapushpi is found throughout India. It consists of phenols, glycosides, tri-terpenoides, steroids, volatile oil, fixed oils, fatty acids, alkaloids, proteins and amino acids and carbohydrates with various chemical constituents such as betaine, shankhapushpine, evolvine, scopoletin, scopolin, umbelliferone, piperine, triacontane, penttrioctane, octodeconoic acids, hexadecanoic acid squalene etc..............
Keywords: Evolvulus, alsinoides, neuropharmacology, marketed formulations.
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Title: Pharmacist As A Consultant
Authors: Sumayya Halim || Raman Dang || Mahaveer Dhobi
Source: International Journal of Pharmaceutical Research and Applications, Volume 3, Issue 2 (July) 2018), PP. 07-09
Abstract: Objective: To understand the term "consultant pharmacist‟ and introduce the responsibilities associated with it. Methods: Consultant pharmacists counsel patients of all age groups, and provide recommendations to physicians or prescribers. They also review the medication regimens, and provide inservice educational programs. Through the valuable work of consultant pharmacists, treatment suggestions are made, taking into account the potential adverse effects and interactions among drug, food and disease. All the untreated or undertreated health concerns of the patients are recognized and can be treated with the help of consultant pharmacists. The entire medication regimen is carefully reviewed, including prescription RX, dietary supplements, herbal products and over the counter drugs, to determine whether the drug is correct with respect
to disease, dosed correctly, and affordable for the patient. Results: Thus, consultant pharmacists have to have the best knowledge of all the drug related aspects including the pharmacology and pharmacognosy of synthetic as well as herbal medicines.
Keywords: Pharmacist; Consultant; Medication regimen; Prescription RX.
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Title: Plant Based Treatment of Hepatotoxicity
Authors: Gayyur Fatima || Mahaveer Dhobi
Source: International Journal of Pharmaceutical Research and Applications, Volume 3, Issue 2 (July) 2018), PP. 10-23
Abstract: Most of the anti-cancer, anti-tumor and other class of synthetic medicines cause severe adverse effects on the health of human beings especially on the liver. Liver is the organ that metabolizes most of the drugs which are administered orally. While metabolizing other drugs, liver gets affected and synthetic medicines become a cause for liver diseases and hepatotoxicity. According to a report of WHO, about 75 % or three quarters of the world's population use herbs and medicinal plants to cure liver diseases. Plant medicines are with low or zero adverse effects and so can be used by many patients for hepatoprotective effects. Some of the plants which are used as hepatoprotectives are Andrographic paniculata, Aegle marmelos, Allium sativum, Gymnema sylvestre, Pyrenthrum indicum, Taraxacum officinale, Berberis lyceum, Bryonia alba, Lycopersicon esculentum, Luffa echinata, Nigella sativa, Ocimum sanctum, Terminalia chebula Tinospora cordifolia, and Zingiber officinale etc. These medicinal plants contain potent phytoconstituents which are of use for the treatment of
hepatotoxicity. Therefore in this review, medicinal plants and herbs are collected which are or can be used in liver diseases including hepatotoxicity.
Keywords: Liver, Diseases, Hepatotoxicity, Hepatoprotectiv plants etc.
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